In this enlightening episode about ketosis, I had the distinct honor of speaking with Dominic D’Agostino, Ph.D., an esteemed Associate Professor at the University of South Florida. He is also a Research Scientist at the Institute for Human and Machine Cognition (IHMC), dedicating his vast expertise towards optimizing the health and resilience of both warfighters and astronauts. His remarkable background, which spans from neuropharmacology to physiology and from neuroscience to medical biochemistry, offers a unique perspective that makes him a thought leader in his fields.
Our in-depth discussion delved into the intricate details of metabolic health, with particular emphasis on the ketogenic diet and its impact on various conditions including epilepsy, cancer, and even Alzheimer’s. Dr. D’Agostino shared invaluable insights into how the body’s metabolism is intimately connected to overall health and well-being, including how ketone supplementation can play a pivotal role in brain health. The conversation didn’t stop there. We further ventured into the intriguing realm of CNS oxygen toxicity, discussing its profound implications on the brain, and the potential therapeutic avenues that might mitigate its effects.
I am confident that our listeners, whether familiar with these topics or just diving into the world of metabolic health, will find immense value in Dr. D’Agostino’s insights. So, grab your headphones, find a cozy spot, and tune into this episode.
Key Points From This Episode:
- Understanding ketosis’ impact on the central nervous system [00:05:30]
- Exploring CNS oxygen toxicity [00:11:20]
- Diving into dietary protocols [00:15:45]
- Importance of self-monitoring and physiological baselines [00:20:40]
- Dominic’s emphasis on journaling for health and training [00:24:50]
- Ketone esters require caution [00:34:40]
- Ketones have neuroprotective effects [00:38:48]
- Exogenous ketones can cause harm [00:45:20]
- Ketones may enhance mental performance [00:55:04]
- Discussing the metabolic health summit [01:23:42]