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By application only · For founders & executives

Miami · Aspen · NYC

Trusted by the top .01%to end burnout, brain fog,and decision fatigue.

Get verifiably on track for peak performance, health optimization, and longevity. Get to know your physiology, the science of optimizing your life, and we'll work with you until your health systems are clear, sustainable, and integrated at the level of your identity.

Apply Now Explore the method
  • 250+ Biomarkers
  • MD-led Concierge medical team
  • 1:1 Evidence-based health coaches
  • 600+ Founders & executives
  • 90 days Verifiable results
  • 14 days To your personalized protocol

Trusted by the best in the world

It’s no exaggeration to say that Andres has changed my life for the better. He is more than a health coach; he’s a life coach.
Jeffrey B. Kindler Jeffrey B. Kindler CEO, Centrexion · Former CEO, Pfizer
Andres remained committed, consistent, and adaptable. His approach was structured and realistic, always keeping in mind what was sustainable for our lifestyle. His data-informed mindset helped us stay motivated and focused.
Joe Poulin Joe Poulin CEO, JPK Capital · Board Member, Airbnb
Andres has done an amazing job for me over a long term programme to gradually transform my health and wellbeing. […] My energy levels have gone through the roof.
Simon Denyer Simon Denyer CEO, PEAK Sport Media · Former CEO, DAZN
Andres was a valuable addition to my professional team during my 2023 season. His methodology is extremely thorough. He helped me achieve all of my fitness and health goals through expertly guided meal planning, health analytics, and glucose monitoring.
Bianca Andreescu Bianca Andreescu Grand Slam Tennis Champion
Trustpilot

TrustScore 4.5 · 24 reviews

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Google

5.0 · 47 Google reviews

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Trustpilot Complete Game Changer “I have a degree in Kinesiology and almost 10 years of exercise experience, yet I still couldn't solve some of the issues Andrés helped me identify and fix. Working with him produced incredible results that I couldn't have achieved on my own. Can't recommend Andrés and his team highly enough. I feel better, look better, and, most importantly, I now have a deeper understanding of my health and physiology that I'll carry with me forward” Matt Mosholder · July 2026 Google “Andres is the real deal! I cannot recommend him enough. He has truly shaped the way I live on a day to day basis. I was always a health conscious individual, but never felt even close to 100% on a daily basis. However with his guidance I realized that I was just scratching the surface of how good I can feel and how productive I can be. The practices he implemented in my life are second to none. And the level of care and attention he has for my health is truly remarkable. If you want to reach your full potential, working with him is a non-negotiable.” Jonathan Feuer · June 2026 Trustpilot BEST of the best “Andres and his team over at Know Your Physio are not only an ELITE group of individuals but are even better people. If you want comprehensive and proven methods to improve your health and life overall. This is the place for you. From improved sleep/recovery to better overall VO2 max, my performance has been objectively heightened to a level I did not know was possible. I recommend Andres and Know Your Physio to anyone looking to better themselves. They are also stand up human beings and treat others as if they would their own family. It is not what you know, but how you care for others. This team checks all of the boxes and I am ecstatic working with them. 10/10” Josh O · March 2026 Trustpilot Strongly recommend Know Your Physio! “As an avid health and wellness advocate, after researching many programs, Know Your Physio is top notch. The team is exceptional and the program yields amazing results. Cannot recommend Andres enough!” Lisa Bronfman · February 2026 Google “I've known Andres and the KYP community for several months now and I can say this is a group of people who take achieving excellence more seriously than any group I've ever been a part of. I wish I would have found them sooner.” Jorge Roman · March 2026 Trustpilot A Life Changing Program “Between a busy career and trying to up my running game, I needed my body to keep up with my life. Inflammation had been a recurring issue and I felt like I was managing symptoms rather than addressing the underlying issue. A friend pointed me towards Know Your Physio and it turned out to be exactly what I was looking for. It shifted the way I think about my health entirely. The whole experience is personalized. The team has a way of making you feel supported without micromanaging you, which I really appreciated. My inflammation is down, my recovery time after workouts has improved noticeably, and I feel sharper overall. This program is the real deal.” Lauren · March 2026 Trustpilot Expensive, but definitely worth it “I enrolled in Andres's 3-month coaching program and want to share my experience for anyone considering it. There were genuinely impressive elements. Andres and his team handled all the logistics seamlessly. They even sent a mobile phlebotomist to my home to draw blood! Kristal was excellent with handling all of my testing for me. The bloodwork and health data (including Oura integration) were reviewed in detail, and I had a highly productive conversation with a physician about the results. Those sessions gave me great insight into my health picture. Where the program shines is in its high-touch, concierge-style approach. I received personalized meal and training plans, responsive communication, and a team that clearly cares about your wellbeing. Andres is genuinely passionate about health and longevity and treated my relationship with care and respect. It is expensive with all of the bells and whistles (think testing, consultations, etc.), however, the results and level of care were well worth the price. I encourage anyone with the desire to be healthier and resources to choose Know Your Physio!” Emily B. · February 2026 Trustpilot If you are on the fence, GET OFF IT “I have been working with Andres for 2 years and it has dramatically changed my life. When I came to Andres, I was lethargic, overweight, and borderline alcoholic. Working with Andres, he was able to gently guide me towards becoming the highest version of myself. First, he got an understanding of my current lifestyle from a place of love and understanding, not judgement. We went through what my ideal physique and physiology could look like with small, compounding changes that actually last. I have tried so many health coaches, personal trainers, nutritionists, dieticians in the past but nobody was able to get me to the point of losing almost 70 lbs. He met me where I am and gave me the tools and tactics to manage my stressors, get my diet in check while still having flexibility to "have fun" and more importantly, he helped me re-wire what "fun" actually feels like. I am healthier, happier and more aligned after working with Andres and the KnowYour Physio team. My testosterone has gone up, I haven't drank alcohol in the last 7 months and I am feeling confident and amazing in my body. If you are on the fence of working with Andres, I would 100% give it a shot and see for yourself what this could do for your overall wellness and vitality. 10/10 would recomment” Deepak Sharma · February 2026 Trustpilot Andres is the person! “I've known Andres for more than a decade. I first met him when he was a young teenager and I was one of his counselors. It's been incredible to watch his growth and see him become the professional, knowledgeable, and genuinely caring person he is today. A few months ago, I decided to work with him on my health and wellness goals, and the results have been outstanding. Through his guidance, personalized recommendations, bloodwork analysis, and comprehensive testing, we made highly targeted and specific changes that led to major improvements in just 2–3 months. My testosterone increased by 30%, my triglycerides dropped by 42%, and my cholesterol went from high to the normal range. What sets Andres apart is not only his technical expertise, but also his ability to connect with people. He is a genuine, charismatic leader who truly cares about helping his clients become the best version of themselves. His approach is practical, data-driven, and tailored to each individual. I would highly recommend Andres to anyone looking to improve their health, performance, and longevity, especially young professionals and business owners who want to optimize their energy, focus, and overall well-being. Working with him has been one of the best investments I've made in my health.” Ian Perchik · June 2026 Trustpilot Writing this a month later: Andres and his team are excellent “I'll be honest… I came into this pretty skeptical. I'm based in New York, working at a startup, and I was running on empty. Poor sleep, constant brain fog, and a lot of stress. When I started Know Your Physio, what won me over quickly was the team. Kacie was warm and responsive from the start, Dr. Joel Wussow is impressive and very approachable. The conversation I had with him about my health data was one of the more eye-opening medical discussions I've had and Andres really cares about building a relationship and holding me accountable. I also appreciated how the team used my Oura metrics to actually shape my plan, and the genetic testing ended up being one of the most valuable parts since I was able to understand what I'm personally predisposed to gave everything a much deeper level of context. Six months later, my sleep scores are consistently in the 90s, my HRV has improved, I've gained muscle, and the brain fog is (nearly) gone!” Gemma Reizman · April 2026 Trustpilot A Life Changing Investment “This program has been a complete turning point in my life. I enrolled in the 6-month program with Know Your Physio, and as I approach the finish line, the transformation in both my mental and physical health is undeniable. The progress has been real, measurable, and powerful. I've been committed to health and fitness for years, but I hit a plateau that I couldn't break on my own. Working with Andres and the KYP team changed that almost immediately. The results spoke for themselves, and more importantly, the knowledge and principles I've gained will stay with me for life. They've not only elevated me, but they've impacted the people around me as well. This isn't just about tracking habits or optimizing routines - though they do that exceptionally well. It's about mastering the fundamentals, taking ownership of your standards, and building yourself into the strongest version of who you're capable of becoming. […]” Daniel Ayala · February 2026 Trustpilot 18+ months of Coaching “I've been working with Andres for over a year and a half. In that time, I've added 10lbs of lean muscle mass, lowered my body fat % substantially, and even lowerd my heart rate to be the low 50s and sometimes, high 40s, but most importantly, have noticed incredible changes in the quality of my mind. I feel awake and alive instead of sluggish and behind. I am able to make better decisions because I know what fuel + habits my brain needs. I have navigated high-levels of stress with grace because I know how to regulate my nervous system. Having someone in your corner to not only craft your workouts, but also one that has a thorough understanding of the brain + psychology means I can get the most out of my business. Not only am I healthier, but my business had its first $100k month recently. That cannot occur without me as a founder being my sharpest. Andres is more to me than just a health coach. He understands me, my goals, and my business. There are times where I seek his counsel beyond health which is the exact kind of coach I think many of us need” Jamey Lee · February 2026 Trustpilot KYP Changed my Life “I started working with Andres through Know Your Physio with one goal: take ownership of my health in a structured, intelligent way. Step one was sleep. We improved it systematically. and The results were both qualitatively felt and quantitatively tracked through biofeedback. That set the foundation. From there, we centralized everything: weight, bloodwork, biometrics — all monitored and organized through technology so nothing was fragmented or guesswork. We sequenced and analyzed my genetic data to understand what to watch for in blood tests and what to proactively optimize. One major breakthrough: discovering a Vitamin B deficiency linked to a methylation-related genetic mutation. Switching to methylated B vitamins was transformative. The change wasn't subtle — it was life-altering. […]” Joseph Stern · February 2026 Trustpilot Game Changer “I first met Andres at a health conference during his presentation. I was intrigued not only by his knowledge but also by his practical ways of approaching health optimization. After connecting with him and having a few conversations I decided to become his client which has been a game changer. Even though I have been a health enthusiast for many years, it was challenging to figure out what actually moves the needle and what is just the latest biohacking trend. With his coaching I was able to put on 20 lbs of muscle in under 6 months and become the strongest I have ever been. I even reached my goal of bench pressing 225 lb and doing muscle ups! But it wasn't just the physical aspect that improved, he was able to answer all of my questions and help me incorporate new routines and habits into into my daily schedule. I gained more energy, focus and confidence which benefited my professional, personal and family life. […]” Martin Musil · March 2026 Trustpilot A must for longevity “Working with Know Your Physio and Andres Preschel has been truly life-changing for me and my family. I've been working with Andres for a few years now, and what stands out most is his focus on building sustainable, long-term habits rather than quick fixes. Slowly and consistently, he helped me implement health practices that became part of my lifestyle, improving my energy, focus, strength, and overall well-being. What makes his approach unique is the combination of science, accountability, and personalization. He doesn't just give you a plan, he teaches you how to understand your own physiology so you can make better decisions independently. He has also worked with my sons and has been instrumental in shaping their health habits at a young age. That, to me, is priceless. If you are looking for real, lasting change and not hype. I highly recommend Know Your Physio.” Eduardo Krajewski · March 2026 Trustpilot Lifetime healthy habits “Andres helped me create healthy habits that have stayed with me long after our program concluded. We worked together for the 6 months prior to my wedding, hoping to lose 20 pounds and manage the wedding planning stress effectively. I lost the weight, yes it took until the week prior to the wedding, but learned so much about my body. Sticking to healthy sleeping patterns, the supplements Andres recommended, I've lost another 30 pounds in the 6 months after my wedding. I highly recommend Andres to anyone who is serious about living a healthier life” david omsky · March 2026 Trustpilot Writing this months later... “I spend a lot of time in the studio and honestly my health was the last thing on my mind for a long time. I had tried a few different programs before but nothing ever really stuck or felt tailored to me specifically. Know Your Physio was a different experience. The genetic testing was the thing that really got me. Finding out what my body is actually wired for and building around that felt way more personal than anything I had done before. My WHOOP data gave me a live look at how I was responding week to week which kept me locked in. Kristel was great the whole way through, always on it and easy to reach. Andres genuinely cares about the people he works with and you can feel that. Sleep is better, energy is up, BMI is down. For anyone who has tried other programs and felt like they were just going through the motions, this one is worth your time.” alec · February 2026 Trustpilot Loved working with Andres “Loved working with Andres. One of the best decisions I've made and investments I've made because the long term health benefits outweigh his cost 100 fold. Very worth it and changed my life.” Adam Wininger · February 2026

Our members see the following improvements from their baselines

600+ Founders and ExecutivesOptimized for Health and Longevity

+18% Average increase in VO₂max The metric most highly correlated with longevity
+28% Average increase in HRV Build resilience and support peak performance
+24% Average increase in sleep efficiency Make more out of every hour you spend in bed
−19% Average decrease in fat mass Get leaner, feel stronger and more confident
−17% Decrease in biological age Turn back the clock on your biology
+12% Average increase in lean body mass Strength that carries into everything you do

99% customer satisfaction · 100% evidence-based and committed to your health optimization journey

Get to know your physio

Choose your protocol.

Your average checkup tests ~30 markers. We check 250+.

Start here · Clarity

Dr. Joel Wussow · Chief Medical Officer

Dr. Joel Wussow · Chief Medical Officer

The Premier Wellness Assessment

Clarity on exactly where your health stands, and the blueprint you need to follow to optimize it.

  • 150+ biomarkers, drawn at home by a licensed phlebotomist
  • Your personal results dashboard
  • 1-on-1 results review with our Cornell- and Columbia-trained Medical Director
  • Add-ons that go deeper: DEXA scan, WHOOP review, genetic panel, a program built by Andrés
Starting at $1,200 Explore the assessment

Clarity + Accountability

Andrés Preschel · CEO, Founder, Physiologist

Andrés Preschel · CEO, Founder, Physiologist

The KYP Health Optimization Experience

Clarity, coaching, accountability, and a lasting transformation.

  • Regular quarterly comprehensive testing, with at-home blood draws
  • Your personal exercise physiologist and biomedical neuroscientist, coaching you, educating you, holding you accountable
  • Full concierge: we book everything, work around your schedule, and build systems realistic and attainable for you and only you
  • Quarterly comprehensive bloodwork and medical assessment with Dr. Joel Wussow
  • A real relationship, the reason the .01% choose us
Starting at $7,200 · One-time Apply Now

Everything + Medical

Andrés Preschel Dr. Joel Wussow

Andrés Preschel · Dr. Joel Wussow

The KYP VIP Concierge Health & Medical Experience

Clarity, coaching, accountability, and your medical care, with Andrés and Dr. Joel side by side.

  • Everything in the KYP Health Optimization Experience
  • Andrés and Dr. Joel Wussow working side by side on your case
  • Full prescription management, functioning as your primary care, in eligible states (FL, GA, NY, CO, AZ, TX)
  • Peptides, hormone optimization (TRT included), GLP-1s and other pharmaceuticals when your data warrants it, prescribed clinically and monitored continuously
$3,600 / month · 6-month minimum Apply Now

The medical side

Yes. We can include peptides,hormones, and pharmaceuticals.

When your data warrants it, our physician-led medical team can fold peptide therapy, hormone optimization (TRT included), GLP-1s and other pharmaceuticals into your protocol: prescribed clinically, monitored continuously, and grounded in your own bloodwork. And the diagnostics never stop: 250+ biomarkers, tested quarterly.

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Why you still feel off

Winning on the outside.Running on empty inside.

Most high performers are winning on the outside, but quietly running on empty on the inside. Imagine closing that gap.

All client stories
Israel Zighelboim Israel Zighelboim Physician Executive · Wharton MBA · Gynecologic Oncologist

−24 lbs Net weight change

“I have not been at this weight and BMI since I was probably in medical school or before.”
−5.0% Body fat +37% VO₂max vs baseline
Read the full case study
Daniel Ayala Daniel Ayala Client story

−15 lbs Net weight loss

“Honestly, my sleep over the past month has been great. My sleep score right now, it’s 90%.”
19.5% Body fat, from ~25% 100% Peak sleep score
Read the full case study

The roadmap

From data to alasting transformation.

  1. 01

    Know exactly where you stand

    Comprehensive testing tells us what’s happening under the hood and what your mind and body need to thrive, while we build a real relationship with you, so the subjective story and the objective data read as one.

  2. 02

    We build your system, and do the heavy lifting

    A chef cooking from your blood work and genetics. A phlebotomist sent to your home for quarterly testing. Every appointment scheduled so you walk in and walk out. Supplements ordered for you. Your home, biohacked. These are things only we do.

  3. 03

    Execute, with accountability

    Coaching and behavior change run side by side with quarterly testing, data analytics, and 24/7 monitoring. We’re in your back pocket: your care team is there whenever you need it.

  4. 04

    A lasting transformation

    Change accomplished at the level of your identity. You’re on track to live your best and your longest, and you know exactly what you need to do to stay there.

An honest comparison

Not your annual checkup.

The KYP Experience Annual physical AI advice Primary care Personal trainer Functional medicine
250+ biomarkers, tested quarterly
A medical team focused on optimization, not illness
1:1 coaching, accountability & behavior change
Concierge: booked, scheduled and delivered for you
A protocol built from your data, not averages
24/7 access and continuous monitoring
Verifiable performance outcomes in 90 days

What that actually feels like

  • No more 2 p.m. crash
  • Present with your family after a long day

By application only

Limited to 50 membersper quarter.

We’re not built to scale, on purpose. Our priority is a real relationship with you, and the biggest possible impact on your life. Know Your Physio is built for founders and executives earning $250K+ who are done guessing.

Apply Now

01

Comprehensive testing

Know, verifiably, exactly where you stand, quarter after quarter.

02

Coaching & accountability

A physiologist and neuroscientist in your corner until the change holds.

03

The concierge experience

We carry the logistics. You carry the results.

“Nobody cares how much you know untilthey know how much you care.”

Theodore Roosevelt

Knowing your physiology, discovering your science, is the best and most reliable way to show up as the ideal version of yourself, with burnout, brain fog, and decision fatigue extinguished.

Andrés Preschel
Andrés Preschel, BSc, MSc(c) Physiologist, Neuroscientist, & CEO

Apply Now